Anne Katrine Kvissel

Associate Professor

Department of Natural Sciences

Email: anne.k.kvissel@uia.no
Phone: +47 38141660
Mobile phone: +4798483963

Office JU062 (Universitetsveien 25, 4630 Kristiansand, Norway)

Areas of responsibility

Education

2006 PhD in Medical Biochemistry (Dep of Basic Medical Sciences, UiO)

2000 MSc in Biotechnology (Griffith University, Australia)

1996 Biomedical Laboratory Scientist (Oslo University College)

Work experience

2015 - - Senior Engineer/ Associate professor (Department of Natural Sciences, UiA)

2013 - - Scientific Editor, Tidsskriftet Bioingeniøren

2011 – 2013 Research scientist (Dep of Molecular Biology, Akershus University hospital)

2006 – 2011 Postdoctoral fellow (Dep of Basic Medical Sciences, UiO)

2008 – 2009 Postdoctoral fellow (Dep of Medical Biochemistry and Microbiology, Uppsala University)

1996 – 2001 Biomedical laboratory scientist (Dep of Clinical Chemistry, Ullevål University Hospital)

Research

Academic interests

Fields of interest

Medical biochemistry, hematology, preanalytical factors, molecular diagnostics, ethics

Furuseth, May-Tove; Kvissel, Anne Katrine; Berg, Vivian; Kjøbli, Eli; Volden, Vivi & Solli, Ann Iren [Show all 12 contributors for this article] (2022). Praksisstudienes omfang og organisering i bioingeniørutdanningen. Bioingeniøren. ISSN 0801-6828. 8, p. 24–29. Full text in Research Archive Show summary
Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer fastsatt. Både tidligere rammeplan og nye retningslinjer har regulert læringsutbyttene og omfang av praksis i utdanningen. I denne studien kartlegges omfang og organisering av praksisstudiene ved de ulike studieprogrammene, dette for å undersøke forskjeller og likheter og tilrettelegge for at studiestedene kan lære av hverandre. Det er innhentet data fra hvert studieprogram for omfang og organisering av veiledet intern praksis, ekstern praksis samt bacheloroppgaven. Dette ble kartlagt for alle studiestedene før og etter innføring av nye retningslinjer. Resultatene viser ulikheter i omfang og organisering av praksisstudiene og bacheloroppgaven mellom studieprogrammene i Norge og da særlig i organisering av intern praksis. De nye retningslinjene åpner samtidig opp for en videre fortolkning av praksisbegrepet og av krav til omfang og organisering av praksis. For å sikre likeverdig sluttkompetanse for ferdigutdannede, uavhengig av studiested, er det behov for i større grad enes om hva som gir tilstrekkelig omfang og god kvalitet i praksis i bioingeniørutdanningen. Denne deskriptive studien viser behov for videre forskningssamarbeid mellom studiestedene, for å utvikle en bioingeniørutdanning av best mulig kvalitet for fremtiden.
Inchley, Christopher; Berg, Are Stuwitz; Vahdani-Benam, Afsaneh; Kvissel, Anne Katrine; Leegaard, Truls Michael & Nakstad, Britt (2017). Mycoplasma Pneumoniae: A Cross-sectional Population-based Comparison of Disease Severity in Preschool and School-age Children. The Pediatric Infectious Disease Journal. ISSN 0891-3668. 36(10), p. 930–936. doi: 10.1097/INF.0000000000001628.
Tunsjø, Hege Smith; Kvissel, Anne Katrine; Follin-Arbelet, Benoit; Brotnov, Beth-Marie; Ranheim, Trond Egil & Leegaard, Truls Michael (2015). Suitability of stx-PCR directly from fecal samples in clinical diagnostics of STEC. APMIS - Journal of Pathologiy, Microbiology and Immunology. ISSN 0903-4641. 123(10), p. 872–878. doi: 10.1111/apm.12428.
Persson, Heidi Törmänen; Aksaas, Anne Kristin; Kvissel, Anne Katrine; Punga, Tanel; Engström, Åke & Skålhegg, Bjørn Steen [Show all 7 contributors for this article] (2012). Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicing. PLOS ONE. ISSN 1932-6203. 7(2). doi: 10.1371/journal.pone.0031871.
Aksaas, Anne Kristin; Eikvar, Sissel; Akusjervi, Goran; Skålhegg, Bjørn Steen & Kvissel, Anne Katrine (2011). Protein kinase A-dependent phosphorylation of serine 119 in the proto-oncogenic Serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein. Genes, Chromosomes and Cancer. ISSN 1045-2257. 2(8), p. 841–851.
Aksaas, Anne Kristin; Larsen, Anja C V; Rogne, Marie; Rosendal, Ken Roger; Kvissel, Anne Katrine & Skålhegg, Bjørn Steen (2011). G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A. Journal of Molecular Signaling. ISSN 1750-2187. 6, p. 1–14. doi: 10.1186/1750-2187-6-10.
Stakkestad, Øystein; Larsen, Anja C V; Kvissel, Anne Katrine; Eikvar, Sissel; Ørstavik, Sigurd & Skålhegg, Bjørn Steen (2011). Protein kinase A type I activates a CRE-element more efficiently than protein kinase A type II regardless of C subunit isoform. BMC Biochemistry. ISSN 1471-2091. 12. doi: 10.1186/1471-2091-12-7.
Jarnæss, Elisabeth; Stokka, Anne Jorunn; Kvissel, Anne Katrine; Skålhegg, Bjørn Steen; Torgersen, Knut Martin & Scott, John D. [Show all 8 contributors for this article] (2009). Splicing Factor Arginine/Serine-rich 17A (SFRS17A) Is an A-kinase Anchoring Protein That Targets Protein Kinase A to Splicing Factor. Journal of Biological Chemistry. ISSN 0021-9258. 284(50), p. 35154–35164. doi: 10.1074/jbc.M109.056465.
Larsen, Anja C V; Kvissel, Anne Katrine; Hafte, Tolesa Tilahun; Avellan, Cecilia I. A.; Eikvar, Sissel & Rootwelt, Terje [Show all 8 contributors for this article] (2008). Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates. The FEBS Journal. ISSN 1742-464X. 275(2), p. 250–262. doi: 10.1111/j.1742-4658.2007.06195.x.
Oksvold, Morten Pedersen; Funderud, Ane; Kvissel, Anne Katrine; Skarpen, Ellen; Henanger, Heidi Hatledal & Huitfeldt, Henrik [Show all 8 contributors for this article] (2008). Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit. BMC Cell Biology. ISSN 1471-2121. 9. doi: 10.1186/1471-2121-9-16.
Kvissel, Anne Katrine; Ramberg, Håkon; Eide, Turid; Svindland, Aud; Skålhegg, Bjørn Steen & Tasken, Kristin Austlid (2007). Androgen dependent regulation of protein kinase A subunits in prostate cancer cells. Cellular Signalling. ISSN 0898-6568. 19(2), p. 401–409. doi: 10.1016/j.cellsig.2006.07.011.
Pedersen, Elena Didenko; Ellingsrud, Elisabeth; Kvissel, Anne Katrine; Pharo, Anne Margrethe; Skålhegg, Bjørn Steen & Rootwelt, Terje [Show all 7 contributors for this article] (2007). Expression of complement regulators and receptors on human NT2-N neurons - Effect of hypoxia and reoxygenation. Molecular Immunology. ISSN 0161-5890. 44(9), p. 2459–2468. doi: 10.1016/j.molimm.2006.10.022. Show summary
Complement activation can cause tissue damage in cerebral stroke by the release of biologically potent activation products and impaired function of regulatory proteins. We investigated the constitutive and hypoxia–reoxygenation-dependent expression of complement receptor 1 (CD35), membrane cofactor protein (CD46), decay-accelerating factor (CD55), protectin (CD59), and complement C3a and C5a receptors (C3aR and C5aR) on human NT2-N neurons. The effect of hypoxia–reoxygenation on C3d-deposition on neurons and endothelial cells was also investigated. NT2-N neurons were examined by cellular enzyme-linked immunosorbent assay and immunofluorescence microscopy. Endothelial cells were examined by flow cytometry. Three hours 1% or 0.1% hypoxia and 21 h reoxygenation with 50% AB-serum were used to investigate the effect of hypoxia–reoxygenation on regulators and C3d-deposition. NT2-N neurons expressed significant amounts of CD59 (Clone H19/Clone BRIC229: p = 0.000006/p = 0.000003), CD46 (p = 0.00006), CD55 (p = 0.003) and C3aR (p = 0.00003). CD35 and C5aR were not significantly expressed. There were no effects of hypoxia–reoxygenation on any of the regulators or receptors after 1% hypoxia and reoxygenation. However, CD55 (p = 0.02) was down-regulated after 0.1% hypoxia and subsequent reoxygenation with AB-serum. There were no difference observed in the C3d-deposition during hypoxia–reoxygenation in either neurons or endothelial cells. In conclusion, human NT2-N neurons constitutively express C3aR, CD46, CD55 and, in particular, CD59. The cells may respond to locally produced C3a and, at the same time, be well protected against complement attack. Although severe hypoxia–reoxygenation may down-regulate CD55 expression, it does not seem to influence C3d-deposition
Kvissel, Anne Katrine; Ørstavik, Sigurd; Eikvar, Sissel; Brede, Gaute; Jahnsen, Tore & Collas, Philippe [Show all 8 contributors for this article] (2007). Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing. PMID: 17594903 [PubMed - in process]. Experimental Cell Research. ISSN 0014-4827. 313, p. 2795–2809. doi: 10.1016/j.yexcr.2007.05.014.
Frøyland, Elisabeth; Pedersen, Elena Didenko; Kvissel, Anne Katrine; Almaas, R; Pharo, Anne Margrethe & Skålhegg, Bjørn Steen [Show all 8 contributors for this article] (2006). Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons. Brain Research. ISSN 0006-8993. 1113, p. 64–73.
Skålhegg, Bjørn Steen; Funderud, Ane; Henanger, HH; Hafte, Tolesa Tilahun; Larsen, Anja Camilla Vogeler & Kvissel, Anne Katrine [Show all 8 contributors for this article] (2005). Protein kinase A (PKA) - A potential target for therapeutic intervention of dysfunctional immune cells. Current Drug Targets. ISSN 1389-4501. 6.
Kvissel, Anne Katrine; Ørstavik, Sigurd; Øistad, P; Rootwelt, Terje; Jahnsen, Tore & Skålhegg, Bjørn Steen (2004). Induction of Cbeta splice variants and formation of novel forms of protein kinase A type II holoenzymes during retinoic acid-induced differentiation of human NT2 cells. Cellular Signalling. ISSN 0898-6568. 16(5), p. 577–587. Show summary
Cyclic AMP (cAMP) and cAMP-dependent protein kinase (PKA) are critical regulators of neuronal differentiation. The expression, levels and activities of PKA subunits were studied prior to and during differentiation of the human neuronal precursor cell line NTera 2 (NT2). Undifferentiated NT2 cells expressed mainly cytoplasmic PKA type I, consisting of the regulatory subunit RIalpha and the catalytic subunit Calpha. Low levels of PKA type II consisting of RIIalpha or RIIbeta associated with Calpha were also detected, mainly in the cytoplasm and in the Golgi-centrosomal area. During retinoic acid-induced differentiation, the RIalpha and RIIalpha expressions remained in the cytoplasm, while we observed a strong upregulation of RIIbeta, located to the whole cytoplasm including neurite extensions. This upregulation coincided with increased PKA-specific activity accompanied by a strong induction of a number of neuronal-specific Cbeta splice variants that together with RIIbeta form novel PKAII holoenzymes. Formation of novel PKAII holoenzymes may imply specific PKA features which may have consequences for the process of neuronal differentiation and nerve cell function

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Kvissel, Anne Katrine (2023). Identifisering av pseudotrombocytopeni på Sysmex XN. Bioingeniøren. ISSN 0801-6828.
Kvissel, Anne Katrine (2023). Det lokale mikrobiomet i tumorvev er assosiert med overlevelse hos pasienter med kolorektal kreft. Bioingeniøren. ISSN 0801-6828.
Kvissel, Anne Katrine; Stormo, Camilla & Engeset, Dagrun (2023). Seminal microbiome. Method optimization for nanopore sequencing jn seminal fluid. A pilot study.
Berg, Kirsti; Kvissel, Anne Katrine; Næss, Marit & Tunsjø, Hege (2021). Bioingeniør - en tittel for evig? Bioingeniøren. ISSN 0801-6828. p. 32–33.
Kvissel, Anne Katrine (2021). Bør klassiske parametere i anemiutredning fjernes? Bioingeniøren. ISSN 0801-6828. p. 26–27.
Kvissel, Anne Katrine (2019). Den pedagogiske verktøykassen blir stadig mer omfangsrik. Bioingeniøren. ISSN 0801-6828. 54(4), p. 5–5.
Kvissel, Anne Katrine (2019). Nordisk utdanningskonferanse om digitalisering og praksis. Bioingeniøren. ISSN 0801-6828. 54(8), p. 17–19.
Kvissel, Anne Katrine (2019). Hvor og hvordan publisere?
Kvissel, Anne Katrine (2018). DROP-TO-DROP VARIATION IN CAPILLARY HAEMOGLOBIN CONCENTRATIONS.
Kvissel, Anne Katrine; Orstavik, S; Eikvar, Sissel; Øistad, Pia Madeleine; Punga, T & Jahnsen, Tore [Show all 9 contributors for this article] (2004). Co-localization and in vitro phosphorylation of splicing factors by cAMP-dependent protein kinase. The FASEB Journal. ISSN 0892-6638. 18, p. C259–C259.
Kvissel, Anne Katrine; Øistad, Pia; Ørstavik, Sigurd; Jahnsen, Tore; Collas, Philippe & Skålhegg, Bjørn Steen (2002). Location of the cAMP-dependent kinase and components of the splicesosome.

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Published Apr. 16, 2024 11:42 AM