ML-314 Applied Molecular Biology
- ECTS Credits:
- 5
- Responsible department:
- Faculty of Engineering and Science
- Course Leader:
- Anne Katrine Kvissel
- Lecture Semester:
- Spring
- Teaching language:
- Norwegian.
- Duration:
- 1 term
The course is connected to the following study programs
- Bachelor's Programme in Biomedical Laboratory Science
Teaching language
Norwegian.Prerequisites
BIO111 (Cell Biology and Genetics) must be passed. Attendance to all mandatory laboratory exercises in ML-208 (Molecular Biology) must be approved and related assignments must be passed.
Recommended prerequisites
ML-208 – Molecular Biology
Course contents
The course provides an overview of some of the wide-ranging applications of molecular methods within diagnostics and personalized medicine. There will be focus methods at the DNA/RNA – level of microbes and human biological material (included tumour tissue) using various molecular techniques, such as PCR, FISH, microarray and sequencing. The students will analyse and interpret real-time PCR data from patient samples and controls. The students will also sequence DNA molecules and analyse the results using relevant bioinformatic tools and databases. They will also use bioinformatics to obtain information about relevant genes and molecules.
Laboratory exercises will provide students with detailed knowledge and experience within selected application areas, including focus on critical prea nalytical factors.
Learning outcomes
On successful completion of the course, the student should:
-
have knowledge about basic and specialized molecular techniques used in medical diagnostics and research
-
have knowledge about quality assurance related to molecular methods used in laboratory medicine
-
know how molecular methods are used in different medical laboratory disciplines, such as pathology, microbiology, medical genetics, medical biochemistry, immunology/transfusion medicine and pharmacology
-
be able to master procedures for independent work in a molecular biology laboratory
-
be able to process PCR data to interpret results from patient samples and controls
-
be able to process and analyse DNA sequences and other collected data using bioinformatics
Examination requirements
Attendance to all mandatory laboratory exercises must be approved and related assignments must be passed. More information will be given in Canvas.
Teaching methods
Instruction is comprised of lectures, a seminar and laboratory exercises. Attendance to the seminar and laboratory exercises is mandatory. More details will be given in the beginning of the semester and in Canvas. The expected workload is approximately 135 hours (including instruction and self-studies) according to “Forskrift om studier og eksamen ved UiA (§13).
Evaluation
The study programme manager, in consultation with the student representative, decides the method of evaluation and whether the courses will have a midterm- or end of term evaluation, see also the Quality System, section 4.1. Information about evaluation method for the course will be posted on Canvas.
Assessment methods and criteria
A 2-hour written examination under supervision, graded assessment.
Reduction of Credits
This course’s contents overlap with the following courses. A reduction of credits will occur if one of these courses is taken in addition:
| Course | Reduction of Credits |
|---|---|
| BIO402 – Applied Molecular Biology | 5 |
| ML-207 – Applied Molecular Biology | 5 |
| ML-317 – Molecular Diagnostics and Bioinformatics | 5 |