John-Kåre Vederhus

• Bjørnestad, Endre Dahlen; Vederhus, John-Kåre & Clausen, Thomas (2024). Change in substance use among patients in opioid maintenance treatment: baseline to 1-year follow-up. Harm Reduction Journal. ISSN 1477-7517. 21(1). doi: 10.1186/s12954-024-01005-x.
• Bjørnestad, Endre Dahlen; Vederhus, John-Kåre & Clausen, Thomas (2024). Change in self-reported somatic symptoms among patients in opioid maintenance treatment from baseline to 1-year follow-up. BMC Psychiatry. ISSN 1471-244X. 24(1). doi: 10.1186/s12888-024-05590-w.
• Gabrielsen, Karin Berle; Clausen, Thomas; Haugland, Siri Håvås & Vederhus, John-Kåre (2024). Gradual improvement in functioning and mental distress during long-term outpatient SUD treatment – A prospective pre-post study. Addictive Behaviors Reports. ISSN 2352-8532. 19, p. 1–8. doi: 10.1016/j.abrep.2024.100525.
• Weimand, Bente Margrethe; Karlsson, Ann Tarja; Solli, Kristin Klemmetsby; Vederhus, John-Kåre; Mordal, Jon & Digranes, Linn Camilla Wergeland [Show all 7 contributors for this article] (2023). Characteristics of opioid-dependent patients choosing antagonist treatment with extended-release naltrexone compared with patients in opioid maintenance treatment in Norway. Heroin Addiction and Related Clinical Problems. ISSN 1592-1638. 25(4), p. 5–14. Show summary

  Background: Opioid dependency is a risk factor for several negative life events and conditions. The opioid receptor inhibitor extended-release naltrexone (XR-NTX) is safe and effective in reducing illicit substance use. Here, we report results of a naturalistic, multicentre, open-label trial of XR-NTX for 24 weeks, with an optional 28-week treatment extension (NaltRec study). Aims: The study aims were to compare sociodemographic and clinical variables between patients choosing XR-NTX (n=162) and those in opioid agonist treatment (OAT) (n= 155), and to compare these variables in the XR-NTX group between patients who were (n= 103) and were not (n= 59) in OAT before study inclusion. Methods: To measure objective-related factors, we used a structured interview at inclusion. Results: The XR-NTX group had fewer women, was younger and reported poorer living and social conditions than the OAT group. Both groups had serious health conditions. Across groups, 40% percent reported lifetime suicide attempts, and 60% reported abusive experiences, with 47% women and 17% men reporting sexual abuse. Age at onset of polydrug use was 20 years. Patients preferring XR-NTX to OAT reported poorer social conditions compared with those choosing OAT. Conclusions: Women and patients who are not stabilized before enrolment need specific attention to tailored supportive measures during treatment with extended-release naltrexone.

• Bjørnestad, Endre Dahlen; Vederhus, John-Kåre & Clausen, Thomas (2022). High smoking and low cessation rates among patients in treatment for opioid and other substance use disorders. BMC Psychiatry. ISSN 1471-244X. 22(1), p. 1–8. doi: 10.1186/s12888-022-04283-6. Full text in Research Archive Show summary

  Background: Smoking is a well-documented cause of health problems among individuals with substance use disorders. For patients in opioid maintenance treatment (OMT), the risk for somatic health problems, including preventable diseases associated with tobacco smoking, increases with age. Our aim was to describe smoking among patients entering substance use disorder (SUD) treatment, investigate changes in smoking from the start of treatment to 1-year follow-up, and explore factors related to smoking cessation. Methods: We employed data from the Norwegian Cohort of Patient in Opioid Maintenance Treatment and Other Drug Treatment Study (NorComt). Participants were 335 patients entering SUD treatment at 21 participating facilities across Norway. They were interviewed at the start of treatment and at 1-year follow-up. The main outcomes were smoking and smoking cessation by treatment modality. A logistic regression identified factors associated with smoking cessation. Results: High levels of smoking were reported at the start of treatment in both OMT (94%) and other SUD inpatient treatment patients (93%). At 1-year follow-up most patients in OMT were still smoking (87%), and the majority of the inpatients were still smoking (69%). Treatment as an inpatient was positively associated and higher age was negatively associated with smoking cessation. Most patients who quit smoking transitioned to smokeless tobacco or kept their existing smokeless habit. Conclusion: As illustrated by the high smoking prevalence and relatively low cessation levels in our sample, an increased focus on smoking cessation for patients currently in OMT and other SUD treatment is warranted. Harm-reduction oriented smoking interventions may be relevant.

• Friesinger, Jan Georg; Haugland, Siri Håvås & Vederhus, John-Kåre (2022). The significance of the social and material environment to place attachment and quality of life: findings from a large population-based health survey. Health and Quality of Life Outcomes. ISSN 1477-7525. 20. doi: 10.1186/s12955-022-02045-2. Full text in Research Archive Show summary

  Background: There is an international public health interest in sustainable environments that promote human wellbeing. An individual’s bond to places, understood as place attachment (PA), is an important factor for quality of life (QoL). The material environment, such as access to nature (AtN), access to amenities (AtA), or noise, and the social environment, such as social support or loneliness, has the potential to infuence PA. The aim of the present study was to explore the relationship between these factors and QoL. Methods: The study relied on data from 28,047 adults from 30 municipalities in Southern Norway obtained from the Norwegian Counties Public Health Surveys in 2019. Latent regression analyses were used to examine the relationship between the material and social environmental factors and QoL, mediated by PA. Results: We found a relationship between social and material environmental factors and PA. Higher AtN and AtA scores were related to an increase in PA, whereas higher perception of noise problems was related to decreased PA scores. When social environment factors were added to the model, they were even stronger predictors of PA and, in turn, QoL through mediated efects. We also found a strong positive association between PA and QoL (unstandard‑ ized β=0.88, 95% CI=0.87–0.90, p<0.001). The whole model explained 83% of the variance in PA and 65% of the variance in QoL. Conclusions: Taken together, the fndings suggest the relevance of material and social environmental factors for PA and QoL. Therefore, research on public health and QoL should include place-sensitive variables.

• Karlsson, Ann Tarja; Vederhus, John-Kåre; Clausen, Thomas; Weimand, Bente Margrethe; Solli, Kristin Klemmetsby & Tanum, Lars Håkon Reiestad (2022). Impact of Impulsivity, Hyperactivity, and Inattention on Discontinuation Rate among Opioid-Dependent Patients Treated with Extended-Release Naltrexone. International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. 19(18), p. 1–8. doi: 10.3390/ijerph191811435. Full text in Research Archive Show summary

  Previous studies have indicated elevated levels of impulsivity, hyperactivity, and inattention (IHI) among opioid-dependent patients seeking outpatient treatment with extended-release naltrexone (XR-NTX). This led us to hypothesize that IHI may be associated with a higher discontinuation rate for XR-NTX treatment. In a group of 162 patients with opioid dependence, discontinuation prior to the full 24 weeks of the study period (six injections and attending the study visit at 24 weeks) occurred in 49% of the patients, primarily in the early stage of treatment. IHI above the clinical cut-off on the adult ADHD self-report scale (ASRS) was not associated with a risk of premature discontinuation. This finding was not altered when controlling for socio-demographics, substance, use and mental health severity. Conclusively, high levels of IHI per se is not contradictive for XR-NTX treatment in regard to concern for premature discontinuation.

• Vederhus, John-Kåre; Rørendal, Malin; Skårdal, Madelene; Næss, Marianne Otterstad; Clausen, Thomas & Kristensen, Øistein (2022). Successful outcomes with low–threshold intervention for cannabis use disorders in Norway - an observational study. PLOS ONE. ISSN 1932-6203. 17(6), p. 1–12. doi: 10.1371/journal.pone.0269988. Full text in Research Archive
• Gabrielsen, Karin Berle; Clausen, Thomas; Haugland, Siri Håvås; Hollup, Stig Arvid & Vederhus, John-Kåre (2022). Infralow neurofeedback in the treatment of substance use disorders: a randomized controlled trial. Journal of Psychiatry & Neuroscience. ISSN 1180-4882. 47(3), p. 222–229. doi: 10.1503/jpn.210202. Full text in Research Archive
• Gallefoss, Lisbeth; Gabrielsen, Karin Berle; Haugland, Siri Håvås; Clausen, Thomas & Vederhus, John-Kåre (2022). Effects of a brief pre‑admission telephone reminder on no‑show and dropout rates in substance use disorder treatment: a quasi‑experimental study. Substance Abuse Treatment, Prevention, and Policy. ISSN 1747-597X. 17(1). doi: 10.1186/s13011-022-00489-9. Full text in Research Archive
• Vederhus, John-Kåre; Haugland, Siri Håvås & Timko, Christine (2022). A mediational analysis of adverse experiences in childhood and quality of life in adulthood. International Journal of Methods in Psychiatric Research. ISSN 1049-8931. 31(1). doi: 10.1002/mpr.1904. Full text in Research Archive Show summary

  Objectives: This study examined associations of three prevalent adverse childhood experiences (ACEs) - parents' problematic alcohol use (PPAU), parental separation/divorce, and lack of support from a trusted adult-with adult quality of life (QoL), and potential mediators of associations. Methods: Data were from a representative survey (N = 28,047) in Norway that assessed ACEs, QoL, and potential mediators: enduring perceptions of childhood hardships (Difficult Childhood Questionnaire; DCQ), current mental distress, and current social isolation. Latent regression analyses examined potential mediators. Results: Each ACE was positively associated with perceptions of childhood as difficult (higher DCQ scores). In turn, ACEs were negatively associated with adult QoL through indirect effects. Lack of support from a trusted adult had the strongest negative association with adult QoL, compared to PPAU and parental separation/divorce. The association between the ACEs and QoL was explained through the mediators of mental distress and social isolation. Conclusions: Of the examined ACEs, lack of support from a trusted adult had the strongest negative impact on adult QoL. Adult support to vulnerable children could potentially ameliorate adult consequences of ACEs. In addition, adults reporting difficulties due to childhood adversities may benefit from therapeutic interventions that address both psychological distress and isolation.

• Karlsson, Ann Tarja; Vederhus, John-Kåre; Clausen, Thomas; Weimand, Bente; Solli, Kristin Klemmetsby & Tanum, Lars Håkon Reiestad (2021). Levels of impulsivity, hyperactivity, and inattention and the association with mental health and substance use severity in opioid-dependent patients seeking treatment with extended-release naltrexone. Journal of Clinical Medicine. ISSN 2077-0383. 10(19), p. 1–9. doi: 10.3390/jcm10194558. Full text in Research Archive Show summary

  The level of impulsivity, hyperactivity, and inattention (IHI) is higher among patients with substance use disorder (SUD) than in the general population. However, the prevalence of such symptoms in patients seeking treatment with an opioid antagonist, such as extended-release naltrexone (XR-NTX), is unknown. We screened 162 patients with opioid use disorder (OUD) seeking treatment with XR-NTX in Norway using the Adult ADHD Self-Report Scale (ASRS) to estimate the prevalence of IHI alongside an assessment of mental and physical health and substance use. Sixty-six patients scored above the clinical cut-off on the ASRS. Higher levels of IHI were significantly associated with a longer history of frequent amphetamine use, current alcohol use, and greater mental distress. Mental distress was the strongest factor associated with higher levels of IHI. The introduction of screening for IHI and mental distress in opioid maintenance treatment and XR-NTX would likely improve the quality of care and enable clinicians to tailor interventions to the needs of patients with high levels of IHI to prevent treatment discontinuation

• Birkeland, Bente; Weimand, Bente; Ruud, Torleif; Maybery, Darryl & Vederhus, John-Kåre (2021). Perceived family cohesion, social support, and quality of life in patients undergoing treatment for substance use disorders compared with patients with mental and physical disorders. Addiction science & clinical practice. ISSN 1940-0632. 16(1), p. 1–9. doi: 10.1186/s13722-021-00252-8. Full text in Research Archive Show summary

  Purpose: Support from family and other social network elements can be important in helping patients to cope with practical and emotional consequences of diseases. The aim of the study was to examine perception of family and social support and quality of life (QoL) in patients undergoing treatment for substance use disorders (SUDs). We compared them with patients in treatment for mental disorders (MDs) and physical disorders (PDs). Methods: We used data from a national multicenter study that recruited patients (N  =  518) from three treatment domains; SUD treatment units, MD treatment units, and PD treatment units (severe neurological conditions or cancer). Data on family cohesion, social support, and QoL were compared across patient groups. In addition, data on health variables was collected. We used a multiple linear regression procedure to examine how health and support variables were associated with QoL. Results: Family cohesion and social support in the SUD and MD groups were rated at similarly low levels, substantially lower than in the PD group. The SUD group exhibited a somewhat lower QoL than did the PD group, but their QoL was still in the near-to-normal range. In contrast, the MD group had markedly low QoL. When examining factors associated with QoL, we found that greater family cohesion and social support were positively associated with QoL. Mental distress was the strongest factor, and was negatively associated with QoL (beta − 0.15, 95% CI  =  − 0.17/− 0.14, p  <  0.001). Conclusion: Service providers need to be aware of the weaker networks and less regulatory family and/or social support available to patients with SUDs. Providers should focus consistently on the social networks of patients and include patients’ families in treatment processes.

• Haugland, Siri Håvås; Olivieira Vieira de Carvalho, Barbara; Stea, Tonje Holte; Strandheim, Arve & Vederhus, John-Kåre (2021). Associations between parental alcohol problems in childhood and adversities during childhood and later adulthood: a cross-sectional study of 28047 adults from the general population. Substance Abuse Treatment, Prevention, and Policy. ISSN 1747-597X. 16. doi: 10.1186/s13011-021-00384-9. Full text in Research Archive Show summary

  Background Adverse childhood experiences (ACE) are related to adverse physical and mental health outcomes. However, few larger studies based on a general population sample with age groups ranging from young adults to elderly have investigated whether parental alcohol problems increase the risk of offspring subjective reports of ACE both during childhood and current adult adversities. The purpose of this study was to examine the associations between parental alcohol problems and adversities during childhood and later in adulthood. Methods The 28,047 respondents were adults (> 18 years old) from the general population who participated in the Norwegian Counties Public Health Survey. The study had a cross-sectional design and included respondents’ evaluations of childhood experiences and current adult adversities. The short version of the Children of Alcoholics Screening Test (CAST-6, cut-off ≥3) measured parental alcohol problems. Multivariable logistic regression was adjusted for gender, age, and education. Results Growing up with parental alcohol problems strongly increased the risk of experiencing a dysfunctional family environment during childhood (odds ratio [OR] 6.84; 95% confidence interval [CI] 6.36–7.36), perceiving childhood as difficult (OR 5.01; 95% CI 4.58–5.49), and reporting a lack of support from a trusted adult (OR 3.07; 95% CI 2.86–3.29). Parental alcohol problems were associated with a modestly increased risk of harmful alcohol use (OR 1.38; 95% CI 1.29–1.48), but the association with struggling with bad memories was strong (OR 4.56; 95% CI 4.17–4.98). Conclusions Parental alcohol problems increased the risk of offspring experiencing adversities during both childhood and adulthood. Providing supportive services to these children and their families and addressing this issue as part of treatment is important to prevent alcohol related harm.

• Vederhus, John-Kåre; Timko, Christine & Haugland, Siri Håvås (2021). Adverse childhood experiences and impact on quality of life in adulthood: development and validation of a short difficult childhood questionnaire in a large population-based health survey. Quality of Life Research. ISSN 0962-9343. 30, p. 1769–1778. doi: 10.1007/s11136-021-02761-0. Full text in Research Archive
• Drivenes, Karin; Vederhus, John-Kåre; Haaland, Vegard Øksendal; Ruud, Torleif; Hauge, Yina Luk & Regevik, Hilde [Show all 8 contributors for this article] (2020). Enabling patients to cope with psychotropic medication in mental health care: Evaluation and reports of the new inventory MedSupport. Medicine. ISSN 0025-7974. 99(1), p. 1–8. doi: 10.1097/MD.0000000000018635. Full text in Research Archive
• Vederhus, John-Kåre; Høie, Magnhild & Birkeland, Bente (2020). One size doesn't fit all: A thematic analysis of interviews with people who have stopped participating in Narcotics Anonymous in Norway. Addiction science & clinical practice. ISSN 1940-0632. 15(18). doi: 10.1186/s13722-020-00191-w. Full text in Research Archive
• Vederhus, John-Kåre; Rørendal, Malin; Bjelland, Cathrine; Skar, Anja Kristin Solheim & Kristensen, Øistein (2020). Can a Smartphone App for Cannabis Cessation Gain a Broader User Group than Traditional Treatment Services? Substance Abuse: Research and Treatment. ISSN 1178-2218. 14, p. 1–9. doi: 10.1177/1178221820902237.
• Drivenes, Karin; Haaland, Vegard Øksendal; Hauge, Yina Luk; Vederhus, John-Kåre; Irgens, Audun Campbell & Solli, Kristin Klemmetsby [Show all 9 contributors for this article] (2020). Discrepancy in ratings of shared decision making between patients and health professionals: A cross sectional study in mental health care. Frontiers in Psychology. ISSN 1664-1078. 11:443, p. 1–10. doi: 10.3389/fpsyg.2020.00443. Full text in Research Archive Show summary

  Background: A defined goal in mental health care is to increase the opportunities for patients to more actively participate in their treatment. This goal includes integrating aspects of user empowerment and shared decision-making (SDM) into treatment courses. To achieve this goal, more knowledge is needed about how patients and therapists perceive this integration. Objective: To explore patient experiences of SDM, to describe differences between patient and therapist experiences, and to identify patient factors that might reduce SDM experiences for patients compared to the experiences of their therapists. Methods: This cross-sectional study included 992 patients that had appointments with 267 therapists at Sørlandet Hospital, Division of Mental Health during a 1-week period. Both patients and therapists completed the CollaboRATE questionnaire, which was used to rate SDM experiences. Patients reported demographic and treatment-related information. Therapists provided clinical information. Results: The analysis included 953 patient-therapist responder pairs that completed the CollaboRATE questionnaire. The mean SDM score was 80.7 (SD 20.8) among patients, and 86.6 (SD 12.1) among therapists. Females and patients that did not use medication for mental health disorders reported higher SDM scores than males and patients that used psychiatric medications (83.3 vs. 77.7; p < 0.001 and 82.6 vs. 79.8; p = 0.03, respectively). Patients with diagnoses involving psychotic symptoms reported lower SDM scores than all the other patients (66.8 vs. 82.3; p < 0.001). The probability that a patient would report lower SDM scores than their therapist was highest among patients that received involuntary treatment (OR 3.2, p = 0.02), patients with treatment durations longer than 2.2 years (OR 1.9, p = 0.001), and patients that required day care or in-patient care (OR 3.2, p = 0.01 and OR 3.2, p < 0.001, respectively). Conclusion: We showed that both therapists and patients reported good SDM experiences in decisional situations, which indicated that SDM was implemented well. However, the SDM scores reported by in-patients and patients with prolonged or involuntary treatments were significantly lower than scores reported by their therapists. Our findings suggested that it remains a struggle in mental health care to establish a common understanding between patients and therapists in decisional processes regarding treatments for some patient groups

• Vederhus, John-Kåre; Kristensen, Øistein & Timko, Christine (2019). How do psychological characteristics of family members affected by substance use influence quality of life? Quality of Life Research. ISSN 0962-9343. 28(8), p. 2161–2170. doi: 10.1007/s11136-019-02169-x.
• Heldal, Anne Taraldsen; Skurtveit, Svetlana; Lobmaier, Philipp Paul K.; Vederhus, John-Kåre & Bramness, Jørgen Gustav (2018). Bruk av medikamenter for alkoholbrukslidelser i Norge 2004–16. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 138(18). doi: 10.4045/tidsskr.18.0383. Full text in Research Archive
• Årseth, Anne Lene; Johannessen, Berit & Vederhus, John-Kåre (2018). No increase in in-patient detoxification completion rates following pre-hospital telephone intervention. Sykepleien Forskning. ISSN 1890-2936. p. 1–16. doi: 10.4220/Sykepleienf.2018.73348.
• Vederhus, John-Kåre & Høie, Magnhild (2018). The Pragmatic Believer – Faith Development and Personal Experiences of a ‘Higher Power’ in Seasoned Members of Narcotics Anonymous . Research in the Social Scientific Study of Religion. ISSN 1046-8064. 29, p. 123–144. doi: 10.1163/9789004382640_008.
• Birkeland, Bente; Weimand, Bente; Ruud, Torleif; Høie, Magnhild & Vederhus, John-Kåre (2017). Perceived quality of life in partners of patients undergoing treatment in somatic health, mental health, or substance use disorder units: A cross-sectional study. Health and Quality of Life Outcomes. ISSN 1477-7525. 15(1). doi: 10.1186/s12955-017-0750-5. Full text in Research Archive
• Pasareanu, Adrian Razvan; Vederhus, John-Kåre; Opsal, Anne; Kristensen, Øistein & Clausen, Thomas (2017). Mental distress following inpatient substance use treatment, modified by substance use; comparing voluntary and compulsory admissions. BMC Health Services Research. ISSN 1472-6963. 17:5, p. 1–9. doi: 10.1186/s12913-016-1936-y. Full text in Research Archive
• Opsal, Anne; Kristensen, Øistein; Vederhus, John-Kåre & Clausen, Thomas (2016). Perceived coercion to enter treatment among involuntarily and voluntarily admitted patients with substance use disorders. BMC Health Services Research. ISSN 1472-6963. 16(1), p. 1–10. doi: 10.1186/s12913-016-1906-4. Full text in Research Archive
• Dunsæd, Frode; Kristensen, Øistein; Vederhus, John-Kåre; Clausen, Thomas & Høie, Magnhild (2016). Standardisert avrusning ved blandingsmisbruk. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(19), p. 1639–1642. doi: 10.4045/tidsskr.16.0308.
• Pasareanu, Adrian Razvan; Vederhus, John-Kåre; Opsal, Anne; Kristensen, Øistein & Clausen, Thomas (2016). Improved drug-use patterns at 6 months post-discharge from inpatient substance use disorder treatment: Results from compulsorily and voluntarily admitted patients. BMC Health Services Research. ISSN 1472-6963. 16:291. doi: 10.1186/s12913-016-1548-6. Full text in Research Archive
• Vederhus, John-Kåre; Clausen, Thomas & Humphreys, Keith (2016). Assessing understandings of substance use disorders among Norwegian treatment professionals, patients and the general public. BMC Health Services Research. ISSN 1472-6963. 16(1). doi: 10.1186/s12913-016-1306-9.
• Vederhus, John-Kåre; Pripp, Are Hugo & Clausen, Thomas (2016). Quality of Life in Patients with Substance Use Disorders Admitted to Detoxification Compared with Those Admitted to Hospitals for Medical Disorders: Follow-Up Results. Substance Abuse: Research and Treatment. ISSN 1178-2218. 10, p. 31–37. doi: 10.4137/SART.S39192.
• Vederhus, John-Kåre; Birkeland, Bente & Clausen, Thomas (2016). Perceived quality of life, 6 months after detoxification: Is abstinence a modifying factor? Quality of Life Research. ISSN 0962-9343. 25(9), p. 2315–2322. doi: 10.1007/s11136-016-1272-z.
• Pasareanu, Adrian Razvan; Opsal, Anne; Vederhus, John-Kåre; Kristensen, Øistein & Clausen, Thomas (2015). Quality of life improved following in-patient substance use disorder treatment. Health and Quality of Life Outcomes. ISSN 1477-7525. 13. doi: 10.1186/s12955-015-0231-7.
• Vederhus, John-Kåre; Rysstad, Ole; Gallefoss, Frode; Clausen, Thomas & Kristensen, Øistein (2015). Kartlegging av alkoholbruk og røyking hos pasienter innlagt i medisinsk avdeling. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(14), p. 1251–1255. doi: 10.4045/tidsskr.14.0848.
• Vederhus, John-Kåre; Zemore, Sarah E.; Rise, Jostein; Clausen, Thomas & Høie, Magnhild (2015). Predicting patient post-detoxification engagement in 12-step groups with an extended version of the theory of planned behavior. Addiction science & clinical practice. ISSN 1940-0632. 10. doi: 10.1186/s13722-015-0036-3.
• Solhaug, Pål; Høie, Magnhild & Vederhus, John-Kåre (2015). Endring i psykisk velvære etter gjennomført 12-trinnsbasert rusbehandling - En sammenligning av dag- og døgnbehandling. Tidsskrift for psykisk helsearbeid. ISSN 1503-6707. 12(1), p. 28–38.
• Vederhus, John-Kåre; Timko, Christine; Kristensen, Øistein; Hjemdal, Bente & Clausen, Thomas (2014). Motivational intervention to enhance post-detoxification 12-Step group affiliation: A randomized controlled trial. Addiction. ISSN 0965-2140. 109(5), p. 766–773. doi: 10.1111/add.12471.
• Vederhus, John-Kåre (2013). Tvangsinnleggelse av rusmiddelavhengige - noen etiske aspekter. In Mesel, Terje & Leer-Salvesen, Paul (Ed.), Makt og avmakt. Etiske perspektiver på feltet psykisk helse. Portal forlag. ISSN 978-82-92712-74-0. p. 242–260.
• Vederhus, John-Kåre; Kristensen, Øistein; Clausen, Thomas & Gossop, Michael (2012). Turn something bad into something good. British Journal of General Practice. ISSN 0960-1643. 62(594), p. 32–32. doi: 10.3399/bjgp12X616382.
• Vederhus, John-Kåre; Hjerkinn, Bjørg & Kristensen, Øistein (2011). Selvhjelpsgrupper for rusmiddelavhengige. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 131(12), p. 1204–1206. doi: 10.4045/tidsskr.11.0068.
• Vederhus, John-Kåre; Timko, Christine; Kristensen, Øistein & Clausen, Thomas (2011). The courage to change: Patient perceptions of 12-Step fellowships. BMC Health Services Research. ISSN 1472-6963. 11. doi: 10.1186/1472-6963-11-339.
• Kunøe, Nikolaj; Lobmaier, Phillip; Vederhus, John-Kåre; Hjerkinn, Bjørg L; Hegstad, Solfrid & Gossop, Michael [Show all 8 contributors for this article] (2010). Retention in naltrexone implant treatment for opioid dependence. Drug and Alcohol Dependence. ISSN 0376-8716. 111(1-2), p. 166–169. doi: 10.1016/j.drugalcdep.2010.03.021.
• Vederhus, John-Kåre; Laudet, Alexandre; Kristensen, Øistein & Clausen, Thomas (2010). Obstacles to 12-step group participation as seen by addiction professionals: Comparing Norway to the United States. Journal of Substance Abuse Treatment. ISSN 0740-5472. 39(3), p. 210–217. doi: 10.1016/j.jsat.2010.06.001.
• Kunøe, Nikolaj; Lobmaier, Phillip; John-Kåre, Vederhus; Hjerkinn, Bjørg; Gossop, Michael & Hegstad, Solfrid [Show all 8 contributors for this article] (2010). Challenges to antagonist blockade during sustained-release naltrexone treatment. Addiction. ISSN 0965-2140. 105(9), p. 1633–1639. doi: 10.1111/j.1360-0443.2010.03031.x.
• Kunøe, Nikolaj; Lobmaier, Phillip; Vederhus, John Kåre; Hjerkinn, Bjørg; Hegstad, Solfrid & Gossop, Michael [Show all 8 contributors for this article] (2009). Naltrexone implants after in-patient treatment for opioid dependence: randomised controlled trial. British Journal of Psychiatry. ISSN 0007-1250. 194(6), p. 541–546. doi: 10.1192/bjp.bp.108.055319.
• Vederhus, John-Kåre; Kristensen, Øistein; Laudet, Alexandre & Clausen, Thomas (2009). Attitudes towards 12-step groups and referral practices in a treatment culture unfamiliar to 12-step ideology; a survey study. BMC Health Services Research. ISSN 1472-6963. 9(147).
• Kunøe, Nikolaj; Lobmaier, Philipp Paul; Vederhus, John Kåre; Hjerkinn, Bjørg; Hegstad, Solfrid & Gossop, Michael [Show all 8 contributors for this article] (2009). Naltrexone implants after in-patient treatment for opioid dependence: randomised controlled trial. British Journal of Psychiatry. ISSN 0007-1250. 194, p. 541–546. doi: 10.1192/bjp.bp.108.055319.
• Vederhus, John-Kåre; Kristensen, Øistein; Laudet, Alexandre & Clausen, Thomas (2009). Attitudes towards 12-step groups and referral practices in a 12-step naive treatment culture; a survey of addiction professionals in Norway. BMC Health Services Research. ISSN 1472-6963. 9. doi: 10.1186/1472-6963-9-147.
• Vederhus, John-Kåre; Kristensen, Øistein; Laudet, Alexandre & Clausen, Thomas (2009). Attitudes towards 12-step groups and referral practices in a 12-step naive treatment culture; a survey of addiction professionals in Norway. BMC Health Services Research. ISSN 1472-6963. 9. doi: 10.1186/1472-6963-9-147.
• Vederhus, John-Kåre; Kristensen, Øistein; Tveit, Helga & Clausen, Thomas (2008). Tolvtrinnsbaserte selvhjelpsgrupper en ressurs i rehabiliteringen av rusmiddelavhengige. Tidsskrift for Norsk Psykologforening. ISSN 0332-6470. 45(10), p. 1268–1275.
• Kristensen, Øistein; Lølandsmo, Terje; Isaksen, Åse; Vederhus, John-Kåre & Clausen, Thomas (2006). Treatment of polydrug-using opiate dependents during withdrawal: towards a standardisation of treatment. BMC Psychiatry. ISSN 1471-244X. doi: 10.1186/1471-244X-6-54.
• Vederhus, John-Kåre & Kristensen, Øistein (2006). High effectiveness of self-help programs after drug addiction therapy. BMC Psychiatry. ISSN 1471-244X. 6. doi: 10.1186/1471-244X-6-35.
• Kristensen, Øistein & Vederhus, John-Kåre (2005). Selvhjelpsgrupper i rusbehandling. Tidsskrift for Den norske legeforening. ISSN 0029-2001. p. 2798–2801.

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• Bjørnestad, Endre Dahlen; Vederhus, John-Kåre & Clausen, Thomas (2022). High smoking and low cessation rates among patients in treatment for opioid and other substance use disorders.
• Vederhus, John-Kåre; Årseth, Anne Lene & Gallefoss, Lisbeth (2017). Kan telefonkontakt før behandling øke oppmøte og redusere frafall i rusbehandling? Erfaringer fra poliklinikk og avgiftningspost ved Sørlandet Sykehus.
• Kristensen, Øistein & Vederhus, John-Kåre (2015). Alkoholforbruk – en naturlig del av anamnesen. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(14), p. 1240–1241. doi: 10.4045/tidsskr.15.0365.
• Vederhus, John-Kåre (2012). – Jeg sier «Jeg er Rita og jeg er rusavhengig» og så svarer de i kor. [Radio]. NRK Rogaland.
• Vederhus, John-Kåre (2012). – Jeg sier «Jeg er Rita og jeg er rusavhengig» og så svarer de i kor. [Internet]. NRK Rogaland.
• Vederhus, John-Kåre (2012). Selvhjelpsgrupper - å vende problemet til en ressurs. Mot rusgift. ISSN 0806-9107. p. 10–13.
• Vederhus, John-Kåre (2012). Patient education to enhance 12-step involvement among patients undergoing detoxification.
• Hjemdahl, Bente; John-Kåre, Vederhus & Clausen, Thomas (2011). Quality of Life (QoL) - Perceived QoL among Patients Admitted to Detox.
• John-Kåre, Vederhus (2011). Selvhjelpsgrupper i rusfeltet – virksomme mekanismer og resultater.
• John-Kåre, Vederhus (2011). Pasienters oppfatning av 12-trinnsgrupper.
• John-Kåre, Vederhus (2011). National differences in acceptance by treatment professionals of Twelve-Step recovery and spirituality.
• John-Kåre, Vederhus (2011). Towards a greater involvement with peer-based resources: addiction-focused self-help groups.
• Kristensen, Øistein; Sundøy, Anders; Skeie, Karin; Vederhus, John-Kåre; Øye, Ingebjørg & Opsal, Anne [Show all 8 contributors for this article] (2009). Short-term treatment of Hepatitis C in heroin-dependent patients. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 129(16), p. 1639–1642.
• Vederhus, John-Kåre; Kristensen, Øistein; Laudet, Alexandre & Clausen, Thomas (2009). Attitudes toward 12-step groups and referral practices in a culture naive to 12-step ideology.
• John-Kåre, Vederhus & Clausen, Thomas (2012). Addiction professionals’ and substance abuse patients’ attitudes towards and usage of 12-step-based self-help groups. Universitetet i Oslo. ISSN 9788282642590.

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